Review papers
Ferroptosis in Health and Disease.
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M Bebber, Kivanc Birsoy, Jan P Böttcher, Simone Brabletz, Thomas Brabletz, Ashley R Brown, Bernhard Brüne, Giorgia Bulli, Alix Bruneau, Quan Chen, Gina M DeNicola, Tobias P Dick, Ayelén Distéfano, Scott J Dixon, Jan B Engler, Julia Esser-von Bieren, Maria Fedorova, José Pedro Friedmann Angeli, Manuel A Friese, Dominic C Fuhrmann, Ana J García-Sáez, Karolina Garbowicz, Magdalena Götz, Wei Gu, Linda Hammerich, Behrouz Hassannia, Xuejun Jiang, Aicha Jeridi, Yun Pyo Kang, Valerian E Kagan, David B Konrad, Stefan Kotschi, Peng Lei, Marlène Le Tertre, Sima Lev, Deguang Liang, Andreas Linkermann, Carolin Lohr, Svenja Lorenz, Tom Luedde, Axel Methner, Bernhard Michalke, Anna V Milton, Junxia Min, Eikan Mishima, Sebastian Müller, Hozumi Motohashi, Martina U Muckenthaler, Shohei Murakami, James A Olzmann, Gabriela Pagnussat, Zijan Pan, Thales Papagiannakopoulos, Lohans Pedrera Puentes, Derek A Pratt, Bettina Proneth, Lukas Ramsauer, Raphael Rodriguez, Yoshiro Saito, Felix Schmidt, Carina Schmitt, Almut Schulze, Annemarie Schwab, Anna Schwantes, Mariluz Soula, Benedikt Spitzlberger, Brent R Stockwell, Leonie Thewes, Oliver Thorn-Seshold, Shinya Toyokuni, Wulf Tonnus, Andreas Trumpp, Peter Vandenabeele, Tom Vanden Berghe, Vivek Venkataramani, Felix CE Vogel, Silvia von Karstedt, Fudi Wang, Frank Westermann, Chantal Wientjens, Christoph Wilhelm, Michele Wölk, Katherine Wu, Xin Yang, Fan Yu, Yilong Zou, Marcus Conrad.
Redox Biology. 2024.
doi: 10.1016/j.redox.2024.103211. PMID: 38908072
Understanding the complexity of p53 in a new era of tumor suppression.
Yanqing Liu, Zhenyi Su, Omid Tavana, Wei Gu.
Cancer cell. 2024.
doi: 10.1016/j.ccell.2024.04.009. PMID: 38729160
International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis.
Xin Chen, Andrey S Tsvetkov, Han-Ming Shen, Ciro Isidoro, Nicholas T Ktistakis, Andreas Linkermann, Werner JH Koopman, Hans-Uwe Simon, Lorenzo Galluzzi, Shouqing Luo, Daqian Xu, Wei Gu, Olivier Peulen, Qian Cai, David C Rubinsztein, Jen-Tsan Chi, Donna D Zhang, Changfeng Li, Shinya Toyokuni, Jinbao Liu, Jong-Lyel Roh, Enyong Dai, Gabor Juhasz, Wei Liu, Jianhua Zhang, Minghua Yang, Jiao Liu, Ling-Qiang Zhu, Weiping Zou, Mauro Piacentini, Wen-Xing Ding, Zhenyu Yue, Yangchun Xie, Morten Petersen, David A Gewirtz, Michael A Mandell, Charleen T Chu, Debasish Sinha, Eftekhar Eftekharpour, Boris Zhivotovsky, Sébastien Besteiro, Dmitry I Gabrilovich, Do-Hyung Kim, Valerian E Kagan, Hülya Bayir, Guang-Chao Chen, Scott Ayton, Jan D Lünemann, Masaaki Komatsu, Stefan Krautwald, Ben Loos, Eric H Baehrecke, Jiayi Wang, Jon D Lane, Junichi Sadoshima, Wan Seok Yang, Minghui Gao, Christian Münz, Michael Thumm, Martin Kampmann, Di Yu, Marta M Lipinski, Jace W Jones, Xuejun Jiang, Herbert J Zeh, Rui Kang, Daniel J Klionsky, Guido Kroemer, Daolin Tang.
Autophagy. 2024.
doi: 10.1080/15548627.2024.2319901. PMID: 38442890
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis.
Zhenyi Su, Yanqing Liu, Lin Wang, Wei Gu.
Genes & Diseases. 2024.
doi: 10.1016/j.gendis.2024.101254.
A guideline on the molecular ecosystem regulating ferroptosis.
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiaofeng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel Schick, Jiao Liu, Dmitry I Gabrilovich, Jinbao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon E Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang.
Nature cell biology. 2024.
doi: 10.1038/s41556-024-01360-8. PMID: 38424270
Deciphering the acetylation code of p53 in transcription regulation and tumor suppression
Z Xia, N Kon, AP Gu, O Tavana, W Gu
Oncogene. 2022.
doi: 10.1038/s41388-022-02331-9. PMID: 35487975
p53 in ferroptosis regulation: the new weapon for the old guardian
Liu Y, Gu W.
Cell Death Differ. 2022.
doi: 10.1038/s41418-022-00943-y. PMID: 35087226
The complexity of p53-mediated metabolic regulation in tumor suppression.
Liu Y, Gu W.
Semin Cancer Biol. 2021.
doi: 10.1016/j.semcancer.2021.03.010. PMID: 33785447
Emerging Mechanisms and Disease Relevance of Ferroptosis.
Stockwell BR, Jiang X, Gu W.
Trends Cell Biol. 2020.
doi: 10.1016/j.tcb.2020.02.009. PMID: 32413317
Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies.
Gutierrez-Diaz BT, Gu W, Ntziachristos P.
Trends Immunol. 2020.
doi: 10.1016/j.it.2020.02.004. PMID: 32139316
Mutant p53 on the Path to Metastasis.
Tang Q, Su Z, Gu W, Rustgi AK.
Trends Cancer. 2020.
doi: 10.1016/j.trecan.2019.11.004. PMID: 31952783
p53 modifications: exquisite decorations of the powerful guardian.
Liu Y, Tavana O, Gu W.
J Mol Cell Biol. 2019.
doi: 10.1093/jmcb/mjz060. PMID: 31282934
Targeting HAUSP in both p53 wildtype and p53-mutant tumors.
Tavana O, Sun H, Gu W.
Cell Cycle. 2018.
doi: 10.1080/15384101.2018.1456293. PMID: 29616860
To be, or not to be: functional dilemma of p53 metabolic regulation.
Wang SJ, Gu W.
Curr Opin Oncol. 2014.
doi: 10.1097/CCO.0000000000000024. PMID: 24240177
Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity.
Shi D, Gu W.
Genes Cancer. 2012.
doi: 10.1177/1947601912455199. PMID: 23150757
p53 post-translational modification: deregulated in tumorigenesis.
Dai C, Gu W.
Trends Mol Med. 2010.
doi: 10.1016/j.molmed.2010.09.002. PMID: 20932800
Modes of p53 regulation.
Kruse JP, Gu W.
Cell. 2009.
doi: 10.1016/j.cell.2009.04.050. PMID: 19450511
How does SIRT1 affect metabolism, senescence and cancer?
Brooks CL, Gu W.
Nat Rev Cancer. 2009.
doi: 10.1038/nrc2562. PMID: 19132007
Dissecting roles of ubiquitination in the p53 pathway.
Shan J, Brooks C, Kon N, Li M, Gu W.
Ernst Schering Found Symp Proc. 2008.
doi: 10.1007/2789_2008_105. PMID: 19202598
p53 ubiquitination: Mdm2 and beyond.
Brooks CL, Gu W.
Mol Cell. 2006.
doi: 10.1016/j.molcel.2006.01.020. PMID: 16455486
Dynamics in the p53-Mdm2 ubiquitination pathway.
Brooks CL, Gu W.
Cell Cycle. 2004.
doi: 10.4161/cc.3.7.997. PMID: 15254415
Dynamics of the p53 acetylation pathway.
Gu W, Luo J, Brooks CL, Nikolaev AY, Li M.
Novartis Found Symp. 2004.
PMID: 15171255
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation.
Brooks CL, Gu W.
Curr Opin Cell Biol. 2003.
doi: 10.1016/s0955-0674(03)00003-6. PMID: 12648672