2015

  1. Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions.

    Qiang L, Kon N, Zhao W, Jiang L, Knight CM, Welch C, Pajvani U, Gu W, Accili D.

    Cell Rep. 2015.

    doi: 10.1016/j.celrep.2015.05.025. PMID: 26074075

  2. Ferroptosis as a p53-mediated activity during tumour suppression.

    Jiang L, Kon N, Li T, Wang SJ, Su T, Hibshoosh H, Baer R, Gu W.

    Nature. 2015.

    doi: 10.1038/nature14344. PMID: 25799988

  3. Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses.

    Jiang L, Hickman JH, Wang SJ, Gu W.

    Cell Cycle. 2015.

    doi: 10.1080/15384101. PMID: 26218928

  4. PCDH10, a novel p53 transcriptional target in regulating cell migration.

    Shi D, Murty VV, Gu W.

    Cell Cycle. 2015.

    doi: 10.1080/15384101. PMID: 25590240

  5. p53 Protein-mediated regulation of phosphoglycerate dehydrogenase (PHGDH) is crucial for the apoptotic response upon serine starvation.

    Ou Y, Wang SJ, Jiang L, Zheng B, Gu W.

    J Biol Chem. 2015.

    doi: 10.1074/jbc.M114.616359. PMID: 25404730

  6. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters.

    Mungamuri SK, Wang S, Manfredi JJ, Gu W, Aaronson SA.

    Oncogene. 2015.

    doi: 10.1038/onc.2014.198. PMID: 25023704

2014

  1. Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombination.

    Rashkovan M, Vadnais C, Ross J, Gigoux M, Suh WK, Gu W, Kosan C, Möröy T.

    Proc Natl Acad Sci USA. 2014.

    doi: 10.1073/pnas.1412107111. PMID: 25468973

  2. Regulation of histone acetyltransferase TIP60 function by histone deacetylase 3.

    Yi J, Huang X, Yang Y, Zhu WG, Gu W, Luo J.

    J Biol Chem. 2014.

    doi: 10.1074/jbc.M114.575266. PMID: 25301942

  3. Controlling ARF stability: new players added to the team.

    Tavana O, Chen D, Gu W.

    Cell Cycle. 2014.

    doi: 10.4161/cc.27786. PMID: 24419106

2013

  1. Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression.

    Chen D, Kon N, Zhong J, Zhang P, Yu L, Gu W.

    Mol Cell. 2013.

    doi: 10.1016/j.molcel.2013.05.006. PMID: 23747016

  2. Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).

    Dai C, Shi D, Gu W.

    J Biol Chem. 2013.

    doi: 10.1074/jbc.M113.476606. PMID: 23677994

  3. RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation.

    Lee JT, Shan J, Zhong J, Li M, Zhou B, Zhou A, Parsons R, Gu W.

    Cell Res. 2013.

    doi: 10.1038/cr.2013.27. PMID: 23419514

  4. The Hunger Games: p53 regulates metabolism upon serine starvation.

    Tavana O, Gu W.

    Cell Metab. 2013.

    doi: 10.1016/j.cmet.2013.01.012. PMID: 23395165

  5. p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.

    Wang SJ, Yu G, Jiang L, Li T, Lin Q, Tang Y, Gu W.

    Cell Cycle. 2013.

    doi: 10.4161/cc.23597. PMID: 23343762

2012

  1. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.

    Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, Rosenbaum M, Zhao Y, Gu W, Farmer SR, Accili D.

    Cell. 2012.

    doi: 10.1016/j.cell.2012.06.027. PMID: 22863012

  2. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence.

    Li T, Kon N, Jiang L, Tan M, Ludwig T, Zhao Y, Baer R, Gu W.

    Cell . 2012.

    doi: 10.1016/j.cell. PMID: 22682249

  3. WTX: an unexpected regulator for p53.

    Dai C, Gu W.

    Mol Cell. 2012.

    doi: 10.1016/j.molcel.2012.02.010. PMID: 22405270

  4. Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice.

    Kon N, Zhong J, Qiang L, Accili D, Gu W

    J Biol Chem. 2012.

    doi: 10.1074/jbc.M111.322867. PMID: 22187431

2011

  1. Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90.

    Dai C, Tang Y, Jung SY, Qin J, Aaronson SA, Gu W.

    Proc Natl Acad Sci USA. 2011.

    doi: 10.1073/pnas.1110988108. PMID: 22084066

  2. Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation.

    Qiang L, Lin HV, Kim-Muller JY, Welch CL, Gu W, Accili D.

    Cell Metab. 2011.

    doi: 10.1016/j.cmet.2011.10.007. PMID: 22078933

  3. A critical role for noncoding 5S rRNA in regulating Mdmx stability.

    Li M, Gu W.

    Mol Cell. 2011.

    doi: 10.1016/j.molcel.2011.08.020. PMID: 21925390

  4. Roles of HAUSP-mediated p53 regulation in central nervous system development.

    Kon N, Zhong J, Kobayashi Y, Li M, Szabolcs M, Ludwig T, Canoll PD, Gu W.

    Cell Death Differ. 2011.

    doi: 10.1038/cdd.2011.12. PMID: 21350561

  5. Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1).

    Liu X, Wang D, Zhao Y, Tu B, Zheng Z, Wang L, Wang H, Gu W, Roeder RG, Zhu WG.

    Proc Natl Acad Sci USA. 2011.

    doi: 10.1073/pnas.1019619108. PMID: 21245319